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Surgical Glue Market

Surgical Glue Market

Surgical Glue Market - Global Industry Assessment & Forecast

Number Of Pages # Pages:


Base Year:



Jun - 2024



Report Code:


Segments Covered
  • By Product By Product Natural Adhesives & Sealants, Synthetic and Semi Synthetic Adhesives & Sealants
  • By Application By Application Central Nervous System, General Surgery, Cardiovascular, Orthopedic, Ophthalmic, Cosmetic, Pulmonary, Urological, Other Applications
  • By Indication By Indication Tissue Sealing, Tissue Engineering, Hemostasis
  • By End User By End User Hospitals, Ambulatory Surgical Centers, Other End Users
  • By Region By Region North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Base YearBase Year: 2023
Forecast YearsForecast Years: 2024 - 2032
Historical YearsHistorical Years: 2018 - 2022
Revenue 2023Revenue 2023: USD 2.55 Billion
Revenue 2032Revenue 2032: USD 6.74 Billion
Revenue CAGRRevenue CAGR (2024 - 2032): 11.5%
Fastest Growing Region Fastest Growing Region (2024 - 2032) Asia Pacific
Largest Region Largest Region (2023): North America
Customization Offered
  • Cross-segment Market Size and Analysis for Mentioned Segments Cross-segment Market Size and Analysis for Mentioned Segments
  • Additional Company Profiles (Upto 5 With No Cost) Additional Company Profiles (Upto 5 With No Cost)
  • Additional Countries (Apart From Mentioned Countries) Additional Countries (Apart From Mentioned Countries)
  • Country/Region-specific Report Country/Region-specific Report
  • Go To Market Strategy Go To Market Strategy
  • Region Specific Market Dynamics Region Specific Market Dynamics
  • Region Level Market Share Region Level Market Share
  • Import Export Analysis Import Export Analysis
  • Production Analysis Production Analysis
  • Other Others Request Customization Speak To Analyst
Surgical Glue Market Share

The global Surgical Glue Market is valued at USD 2.55 Billion in 2023 and is projected to reach a value of USD 6.74 Billion by 2032 at a CAGR (Compound Annual Growth Rate) of 11.5% between 2024 and 2032.

Key Highlights of Surgical Glue Market

  • The North American continent led the Surgical Glue market in 2023, with 39.2% of the total market share,
  • The Asia Pacific region is projected to remain the fastest-growing region throughout the forecast period,
  • In 2023, the Natural Adhesives and Sealants segment, from the segmentation of Product, dominated the market, with a market share of around 62.2%,
  • The General Surgery segment, of the Application segmentation, took the lead in the market, contributing 18.1% of revenue share in 2023,
  • Based on the End User segmentation, the Hospitals segment significantly contributed to the market’s expansion, constituting over 54.2% of the overall revenue share in 2023,
  • The field of tissue engineering and regenerative medicine is expanding, with Surgical Glue playing a pivotal role in the repair and regeneration of tissues. These glues support cell adhesion and proliferation, making them valuable in complex surgeries and tissue reconstruction.

Surgical Glue Market Size, 2023 To 2032 (USD Billion)

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Surgical Glue Market: Regional Overview

In 2023, the North America Surgical Glue market asserted a significant dominance, capturing 39.2% of the total revenue share. This commanding position is driven by several factors poised to fuel market growth, including the escalating number of surgical procedures driven by road accidents, trauma cases, and chronic diseases necessitating surgical interventions. Moreover, the region's market expansion is bolstered by the surge in product approvals, exemplified by Advanced Medical Solutions Group plc's FDA 510(k) clearance for LiquiBand XL in May 2022. This innovative device, comprising a surgical mesh & LiquiBand glue, facilitates the closure of longer wounds while fortifying the seal to mitigate infection risks. With commercial launch projections for 2023 following expected regulatory clearance by the end of 2022, the anticipation of further FDA approvals, such as for AMS's high scheduled gelling antimicrobial product, underlines the key role that the region plays in driving market development.

U.S. Surgical Glue Market Overview

The U.S. Surgical Glue market surged to a valuation of USD 0.82 Billion in 2023, with forecasts indicating a meteoric rise to approximately USD 1.93 Billion by 2032. A significant Compound Annual Growth Rate (CAGR) of 10% from 2024 to 2032 is projected in this forecast. Regulatory oversight from entities like the Food and Drug Administration ensures adherence to stringent safety, efficacy, and quality standards, shaping the market landscape. Such regulatory bodies play a pivotal role in overseeing clinical trials and granting marketing approval for surgical sealants & adhesives. In June 2023, the FDA authorized the Pre-Market Approval (PMA) of LiquiBandFix8, a breakthrough device incorporating Cyanoacrylate adhesive, designed for hernia surgery, exemplifying the regulatory strides driving innovation and advancement within the U.S. Surgical Glue market.

Surgical Glue Market: Product Overview

The Natural Adhesives and Sealants segment dominated the Global Surgical Glue market in 2023, with 62.2% of revenue share. Based on Product, the Global Surgical Glue market is segmented into Natural Adhesives and Sealants and Synthetic and Semi Synthetic Adhesives and Sealants. The Natural Adhesives and Sealants segment emerged as the dominant force in the Global Surgical Glue market, capturing the largest revenue share. This commanding position owes itself to the extensive utilization of several natural sealants in medical applications. Notably, fibrin sealants have demonstrated effectiveness across diverse surgical fields, encompassing thoracic, cardiovascular, orthopedic, neuro, and reconstructive procedures. FDA approval for fibrin's multifaceted usage as sealants, hemostats, and adhesives is poised to catalyze heightened demand for fibrin products, thereby propelling the segmental growth. Meanwhile, the synthetic & semi-synthetic segment is forecasted to exhibit the most rapid expansion over the projection period, buoyed by escalating demand for cyanoacrylates, facilitated by their rapid drying properties.

Key Trends

  1. The benefits of minimally invasive surgery, such as shorter recovery time, less pain & smaller scars, are growing in popularity. In these procedures, surgery glues provide an effective wound closure which does not require the use of sutures and staples.
  2. The development of biodegradable & bioabsorbable Surgical Glue is a major trend. Such glues are designed to be absorbed by the body over time, reducing the need for follow-up surgeries to remove them and minimizing the risk of adverse reactions.
  3. Market growth is facilitated by more stringent regulatory approval of new Surgical Glue. The availability and use of these products in clinical practice is increasing as more products are approved by health authorities such as the FDA and the EMA.
  4. Increased healthcare expenditure and improvements in health infrastructure, particularly in developing countries, are leading to a growing market for Surgical Glue. Better access to advanced healthcare products and surgical procedures is responsible for the growth of this market.
  5. Innovation & market penetration are fostered through cooperation between medical device companies, research institutions and healthcare providers. The development of advanced Surgical Glue products and their application in different medical fields is resulting from these partnerships.
  6. Patient safety and the reduction of post operative complications are becoming increasingly important. For their ability to minimize the risk of infection, reducing inflammation and improving healing, surgery glues are a safer option compared with traditional suture techniques.
  7. The aging population and rising disposable incomes are contributing to the growth of the Surgical Glue market. An older population typically requires more surgical procedures, and higher disposable incomes allow for greater expenditure on advanced medical treatments.

Breakthroughs in the Global Surgical Glue Market

  • WHO's Global Efforts to Enhance Surgical Safety: WHO's initiatives, rooted in the "Safe Surgery Saves Lives" challenge, focus on defining safety standards and implementing measures to improve surgical care worldwide. By addressing areas like surgical site infection prevention, safe anesthesia, and surgical team protocols, WHO aims to enhance patient safety & standardize surgical practices globally.
  • Johnson & Johnson's Global Surgery Initiative Addresses Unmet Surgical Needs: The Global Surgery Initiative by Johnson & Johnson, launched at the 75th World Health Assembly, aims to enhance surgical care across critical areas like obstetric fistula and long bone fractures. The initiative aims at streamlining the supply chain, reducing costs and strengthening healthcare systems to meet local needs by means of pilot programs in Kenya and Malawi with governments, academia and NGOs.
  • FDA's Regulatory Framework for Tissue Adhesives Ensures Safety and Effectiveness: In order to guarantee the safety and effectiveness of tissue adhesives for wound closure devices, specific controls are laid down in the regulatory framework of the FDA. Manufacturers can obtain a timely clearance of their products by complying with these checks, ensuring patient safety and the advancement of wound closure techniques.
  • NICE Guidance Promotes Cyanoacrylate Glue for Hernia Repair: NICE's endorsement of cyanoacrylate Surgical Glue as a fixation method for hernia repairs offers a groundbreaking alternative to mechanical fixation and fibrin glue. Through comprehensive evaluation and data synthesis from 15 clinical trials, NICE's guidance supports the use of cyanoacrylate glue, highlighting its efficacy in reducing post-operative complications & chronic pain.
  • VeraSeal: FDA Authorization for Improved Surgical Hemostasis: VeraSeal, a sealant used to control bleeding during surgery, has received authorization from the European Medicines Agency (EMA) for use in the EU. With demonstrated efficacy in reducing blood loss and shortening hospital stays, VeraSeal represents a significant advancement in surgical hemostasis.
  • Advancements in Biodegradable Hydrogel Adhesives: UCLA-led research has developed a biodegradable hydrogel adhesive inspired by mussel adhesion mechanisms. A promising solution for closing surgical wounds, especially curved and wet tissues, is offered by this adhesive with its superior strength and precision sealing capabilities.

Premium Insights

Achieving effective tissue closure post-operation is crucial for restoring tissue structure and function. Postoperative leakages, occurring in 3% to 15% of cases, pose significant risks and are responsible for a third of postoperative deaths. Surgical sealants & adhesives play a pivotal role in improving patient outcomes by mitigating the risk of complications such as leakages, thereby reducing the length of stay and mortality rates.

Modern surgery is being strongly influenced by rapidly developing medical glues, especially in reducing anastomotic leakage. As a result, in order to replace traditional sealing methods such as sutures, wires and staples, there is a significant increase in their use. The necessity of surgical adhesives is illustrated by the inefficiency of these common methods, such as time waste, tissue trauma and difficulty in applying them to specific surgical sites.

The ability to seal quickly and effectively, in spite of the limitations of traditional techniques, is provided by surgeons' sealants. The growing demand for surgical services worldwide, as well as increasing concerns about post operative wound infections, are driving this shift towards surgical adhesives. Surgery stands as the primary therapeutic option for alleviating disabilities and reducing mortality rates from common conditions. World Health Organization estimates that surgical interventions contribute to approximately 13% of the world's total disability-adjusted life years, emphasizing the critical role of advancements in surgical techniques and materials.

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Market Dynamics

The Surge in Popularity for Synthetic & Semi-Synthetic Surgical Adhesives Drives the Market.

The market for Surgical Glue is increasingly driven by the preference for synthetic and semi-synthetic variants. Such glues are favored for their cost-effectiveness, better adhesion properties, and the reduced risk of adverse reactions. Practical challenges, including tissue damage and the risk of infection, often arise from traditional wound closure techniques such as suturing or stapling. On the other hand, Surgical Glue are a reliable alternative that minimizes tissue trauma and promotes faster healing. The demand for both natural as well as synthetic biomedical adhesives is on the rise, given their safety and compatibility with internal organs, tissues, body fluids, and blood. A key factor contributing to their increasing popularity is the exceptional ability of surgical adhesives to prevent fluid leakage during and after surgery. As a result, the market for Surgical Glue is expanding quickly and R&D efforts are being carried out to improve its properties and safety.

Advancement in Biocompatibility & Application of Surgical Glue Propels the Market

The Surgical Glue market has seen significant advancements aimed at overcoming the limitations of traditional wound sealing techniques. Derived from natural biopolymers like gelatin, collagen, chitosan, albumin, and fibrin, Surgical Glue offer superior biological and physical properties, making them increasingly popular among surgeons. Such glues are now widely used in a variety of surgical procedures, including orthopedic, cardiovascular, ophthalmic, gastrointestinal, periodontal, and reconstructive surgeries. Innovations in this market focus on enhancing the biocompatibility of Surgical Glue, ensuring they integrate seamlessly with the body's tissues, and improving their overall efficacy. Increased awareness of the benefits of Surgical Glue, such as reduced recovery times & lower risk of infection, is driving their adoption globally. The growing number of surgical procedures worldwide further propels the market, as Surgical Glue offer a less invasive and more efficient wound closure method compared to traditional sutures & staples.

Competitive Landscape

  • The Surgical Glue market is characterized by continuous development driven by innovations, strategic acquisitions, and collaborative efforts aimed at achieving market dominance.
  • Baxter International Inc., a leading global medical products company, completed its acquisition of Seprafilm Adhesion Barrier and related assets from Sanofi for $350 million. Seprafilm, which helps reduce adhesions in pelvic and abdominal surgeries, has a significant commercial presence in the U.S., Japan, China, South Korea, France, and other countries.
  • Furthermore, Baxter International Inc. announced the acquisition of the PerClot Polysaccharide Hemostatic System from CryoLife Inc. for up to $60.8 million, with $25 million paid upfront and additional payments contingent on achieving specific milestones. This acquisition aligns with Baxter’s strategy to enhance its advanced surgery portfolio by acquiring complementary and augmentative products and technologies for use across hospitals, including operating rooms.

Recent Market Developments

  • In September 2023, Advanced Medical Solutions (AMS) signed an agreement with TELA Bio, Inc. to commercialize LiquiBandFix8® in the U.S. under the brand name LIQUIFIX™. TELA Bio, known for its fast-growing presence in the U.S. market, specializes in products that address the limitations of current reinforcement materials used in hernia repair, abdominal wall reconstruction, and plastic reconstructive surgery.
  • In April 2023, Baxter International Inc. introduced several new products at the Association of peri-Operative Registered Nurses (AORN) Global Surgical Conference & Expo 2023. Highlights include the launch of the Baxter Patient Warming System, the Helux Pro Connected Surgical Light, and the Floseal + Recothrom flowable hemostat. These innovations were showcased at Baxter’s booth.
  • In February 2023, Advanced Medical Solutions Group plc, a global leader in tissue-healing technologies, acquired Connexicon Medical Limited, a specialist in tissue adhesive technology. The acquisition involved an initial payment of €7 million, with additional payments contingent on achieving specific research, development, regulatory, as well as commercial milestones between 2023-2027. This strategic move bolsters AMS's position in the $300 million global tissue adhesive market, expands its product portfolio, and significantly enhances its capabilities in cyanoacrylate technology.

The global Surgical Glue market can be categorized as Product, Application, Indication, End User, and Region.

Parameter Details
Segments Covered

By Product

  • Natural Adhesives & Sealants
    • Fibrin Sealants
    • Collagen-based Adhesives
    • Gelatin-based Adhesives
  • Synthetic and Semi Synthetic Adhesives & Sealants
    • Cyanoacrylates
    • Polymeric Hydrogels
    • Urethane-based Adhesives

By Application

  • Central Nervous System
  • General Surgery
  • Cardiovascular
  • Orthopedic
  • Ophthalmic
  • Cosmetic
  • Pulmonary
  • Urological
  • Other Applications

By Indication

  • Tissue Sealing
  • Tissue Engineering
  • Hemostasis

By End User

  • Hospitals
  • Ambulatory Surgical Centers
  • Other End Users

By Region

  • North America
    • U.S.
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Regions & Countries Covered
  • North America - (U.S., Canada, Mexico)
  • Europe - (U.K., France, Germany, Italy, Spain, Rest Of Europe)
  • Asia Pacific - (China, Japan, India, South Korea, South East Asia, Rest Of Asia Pacific)
  • Latin America - (Brazil, Argentina, Rest Of Latin America)
  • Middle East & Africa - (GCC Countries, South Africa, Rest Of Middle East & Africa)
Companies Covered
  • Baxter International Inc. (U.S.)
  • B. Braun SE (Germany)
  • Johnson & Johnson Corp. (U.S.)
  • Medtronic PLC (UK)
  • Vivostat A/S (Denmark)
  • CryoLife Inc. (U.S.)
  • OptMed Inc. (U.S.)
  • Ocular Therapeutix Inc. (U.S.)
  • Cohera Medical Inc. (U.S.)
  • Advanced Medical Solutions Group PLC (UK)
  • Integra Lifesciences Pvt. Ltd. (India)
Report Coverage Market growth drivers, restraints, opportunities, Porter’s five forces analysis, PEST analysis, value chain analysis, regulatory landscape, technology landscape, patent analysis, market attractiveness analysis by segments and North America, company market share analysis, and COVID-19 impact analysis
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Frequently Asked Question
  • The global Surgical Glue valued at USD 2.55 Billion in 2023 and is expected to reach USD 6.74 Billion in 2032 growing at a CAGR of 11.5%.

  • The prominent players in the market are Baxter International Inc. (U.S.), B. Braun SE (Germany), Johnson & Johnson Corp. (U.S.), Medtronic PLC (UK), Vivostat A/S (Denmark), CryoLife Inc. (U.S.), OptMed Inc. (U.S.), Ocular Therapeutix Inc. (U.S.), Cohera Medical Inc. (U.S.), Advanced Medical Solutions Group PLC (UK), Integra Lifesciences Pvt. Ltd. (India).

  • The market is project to grow at a CAGR of 11.5% between 2024 and 2032.

  • The driving factors of the Surgical Glue include

  • North America was the leading regional segment of the Surgical Glue in 2023.