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Bone Graft Substitutes Market Trends, Growth & Innovations (2025–2035)

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Bone Graft Substitutes Market

Bone Graft Substitutes Market Size, Share & Trends Analysis Report by Material Type (Allograft, Synthetic, Composites, Polymers, Bone Morphogenic Proteins (BMP)) by Application (Craniomaxillofacial, Dental, Foot & Ankle, Joint Reconstruction, Long Bone, Spinal Fusion) by Region (North America, Europe, Asia Pacific, Latin America, Middle East & Africa) - Global Industry Assessment (2018 - 2023) & Forecast (2024 - 2032)

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Revenue Insights

Revenue 2021

USD 2.7 Billion

Revenue 2028

USD 3.8 Billion

CAGR Revenue

6.75%

Revenue 2024

USD 4.04 Billion

Revenue 2035

USD 8.26 Billion

CAGR Revenue History

5.9%

Largest Region

North America

MSA Largest Region

42.6%

Fastest Region

Asia Pacific

Map Revenue

USD 1.72 Billion

Overview


Market Synopsis:


The Global Bone Graft Substitutes Market was valued USD 2.7 Billion in the year 2021 and is anticipated to reach a value of USD 3.8 Billion by the year 2028. The Global Market is forecasted to grow to exhibit a Compound Annual Growth Rate (CAGR) of 6.75% over the forecast period.


Bone Graft Substitutes are biologics used as an alternative to autologous bone grafts i.e., obtained from the same individual. These substitutes can treat bone, spinal fission defects, and union or non-union surgeries. These substitutes are also used in sports, trauma, plastic, and facial surgeries. In addition, these substitutes have various benefits, such as safety, biocompatibility, and osteoconductivity to fractured bones.

The primary growth attributes of bone graft substitutes are the increasing incidence of bone diseases such as bone infections and tumors. The use of synthetic substitutes such as polymer and ceramics is helping in the adoption of these procedures.


Decreased risk in complex systems is also helping in market growth. COVID- 19 had negatively affected this industry. The primary reasons were lower patient volumes in hospitals and clinics and delayed significant surgeries due to the COVID-19 pandemic. Moreover, the supply of these substitutes was also hindered due to the lockdown. With the lockdowns and restrictions easing up, it is expected that the market will start continuing to grow. However, the higher cost of surgeries and ethical grafting issues are also limiting this industrys growth. Although the major players are investing in Research and Development (R&D) activities in bone grafts and their substitutes, the increase in demand for these surgeries in the geriatric population is expected to help the industry grow in the upcoming years. These substitutes are also increasingly adopted for dental implants. These substitutes help increase the jawlines height and thickness, which is essential for restoring standard dimensions of the jawline.



Market Segmentation:


The Bone Graft Substitute Market is segmented into


Material Type, Application


and


Region


. Based on Material Type, the market is further segmented into Allograft, Synthetic, Composites, Polymers, and Bone Morphogenic Proteins. Furthermore, based on Application, the market is further divided into Craniomaxillofacial, Dental, Foot & Ankle, Joint Reconstruction, Long Bone, and Spinal fusion.



Based on Material Type:


Due to an increase in product introductions, the synthetic sector is predicted to hold most of the market share. Allograft use is expanding due to its advantages, including osteo conductivity and rapid structural support. These are frequently applied to the knee, hip, and spine. Additionally, it is anticipated that the regions increasing prevalence of bone problems will increase demand for the product. These elements might accelerate segmental expansion. Synthetic grafts have the advantages of being readily available, sterile, and having lower morbidity. Additionally, there is no risk of disease transmission, and synthetic bone grafts have a longer shelf life.



Based on Application:


The market is divided into long bone, spinal fusion, foot and ankle, joint repair, craniomaxillofacial, and dental segments based on application. Additionally, the growing elderly population more susceptible to orthopedic conditions is driving up demand for corrective surgery, which is expected to accelerate market growth in the near future. Due to the rise in hip and knee replacement surgeries, the Joint Reconstruction market is anticipated to develop steadily over the coming years. In addition, the projected period predicted that the segment would benefit significantly from rising graft utilization for Dental treatments. Therefore, the long bone section is projected to experience significant expansion in the years to come.



Asia Pacific is projected to Grow at the Highest CAGR during the Forecast Period


The projection term is expected to see profitable growth in the Asia Pacific. The rise in medical tourism and helpful government measures are responsible for this expansion. On the other hand, stringent regulatory rules constrain adoption in some countries. For instance, in South Korea, the Korean Food and Drug Administration must approve the product before it can be marketed (KFDA). The Therapeutic Goods Administration oversees the items in Australia (TGA). Japans rigorous regulatory environment hampers the introduction of international players. Nevertheless, the increased frequency of arthritis and the growing senior population in Asia is predicted to increase demand for the product. Substantial brand presence expansion investments may also help the industry grow.



Competitive Landscape:


The key players in the Global Bone Graft Substitutes market include- Sonoco Products Company, Cryopak Europe, Pelican BioThermal, Cold & Co, ACH Foam Technologies Inc., Saeplast, AccsA’tech, Insulated Products Corporation, TKT GmbH, Snyder Industries, Envirotainer AB, and others.



Segmentation of the Global Bone Graft Substitutes Market:


Renewable Power Market size, 2023 to 2032(USD Billion)

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Market Segmentation

ParameterDetails
Material TypeBy Material Type
  • Allograft (12.3%)
  • Synthetic (43.1%)
  • Composites (28.3%)
  • Polymers (14.1%)
  • Bone Morphogenic Proteins (BMP) (2.2%)
ApplicationBy Application
  • Craniomaxillofacial
  • Dental
  • Foot & Ankle
  • Joint Reconstruction
  • Long Bone
  • Spinal Fusion
RegionBy Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Historical & Forecast Data

Base Year

2023

Historic Year

2018 - 2022

Forecast Year

2023 - 2032

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